Acute infectious lymphocytosis as a T-cell lymphoproliferative syndrome.

Acute infectious lymphocytosis.

Only three cases of infectious lymphocytosis have been described as such in the English literature. Elsewhere about 70 cases have been described, almost entirely in the American literature. As the disease may be more common in England than the recorded'cases would seem to indicate, it was thought worthwhile to report a case, review the literature and discuss the differential diagnosis with part...

Acute infectious lymphocytosis.

Autoimmune Lymphoproliferative Syndrome Misdiagnosed as Hemophagocytic Lymphohistiocytosis A Case Report

Autoimmune lymphoproliferative Syndrome (ALPS) is a rare inherited disorder of apoptosis. It usually presents with chronic lymphadenopathy, splenomegaly, and symptomatic cytopenia in a child. Herein, we report a 14-year-old boy with symptoms misdiagnosed as hemophagocytic lymphohistiocytosis who was treated before ALPS was diagnosed for the patient. This case should alert pediatricians to consi...

Infectious Lymphocytosis

various changes have been noted in the lymphatic system during infection. The paper by Sprunt and Evans2 in 1920 and the subsequent discovery twelve years later of heterophile antibodies in the serum of patients with infectious mono-nucleosis3 stimulated renewed interest in the problem. Data from most laboratories show that the leucocytes rarely pass a level of 20,000 and that there is an "incr...

Fulminant EBV(+) T-cell lymphoproliferative disorder following acute/chronic EBV infection: a distinct clinicopathologic syndrome.

This study describes the clinicopathologic features of 5 patients who developed a fulminant Epstein-Barr virus (EBV)-positive clonal T-cell lymphoproliferative disorder (LPD) after acute EBV infection. One additional patient developed a similar disorder in the setting of long-standing chronic active EBV infection. Detailed immunophenotyping, in situ hybridization for EBV early RNA-1 (EBER1) and...